Hair Loss with Male Pattern Baldness

Normally, about 10-15% of follicles are in the telogen phase. With the onset of male pattern hair loss, this number can increase to 20% or more. The shift occurs when a type of androgen hormone, dihydrotestosterone, or DHT, binds to hormone receptors on the dermal papillae of hair follicles. When DHT contacts a hormone receptor in the dermal papilla, it activates pattern hair loss by disrupting the normal growth cycle.

The affected follicle spends more time in the resting (telogen) phase, has a shorter growth (anagen) phase, and it physically shrinks in size and diameter and fails to grow. The follicle is still alive and connected to the blood supply, but its hair producing ability is diminished. As a consequence, hair production slows, weaker and shorter hair is produced, and some follicles shut down completely. The shorter growth cycle causes more hairs to be shed than are produced, which causes balding to begin and become more obvious.

 

 

 

 

 

 

 

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