The Genetic Component of Male Pattern Baldness

Genetic material within each cell is stored in chromosomes. Among the 23 pairs, males have one X and one Y sex chromosome, whereas females have two X chromosomes. The androgen receptor gene resides on X chromosomes, but the genetic component of male pattern baldness is not as simple as once believed. People once thought that if your grandfather on your mother’s side was balding, you had a 50% chance of inheriting the trait – and here’s why.

Your grandfather is male, so he has one X and one Y chromosome. Your mother is female, so she inherited two X chromosomes: one from your grandfather and one from your grandmother. You inherited one of her X chromosomes, so you have a 50% chance that you received the X chromosome with the balding trait that came from your grandfather. However, more recent evidence suggests that a variety of genetic and environmental factors may be involved. A person whose father is bald is also very likely to lose their hair, and the genetic component for this is not completely understood.

 

 

 

 

 

 

 

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